I don’t know if it’s a yes/no kinda situation – the thing is you have to know your guitar. I can remember Richard being asked this question (pre- SCGC string days) and his response was pretty basic. Try it, but keep a close eye on your guitar. If you notice the action raising, the belly raising, the neck bowing, or any other problem that might indicate excessive string tension, then you need to lower the tension. So, don’t put them on and slide the guitar under your bed and wait to check it in 6 months. There will be some extra tension, so you may need to make a minor adjustment initially, but after that, if it continues to show problems, you’re probably better off going back to lights –
That said, the minimal extra tension from SCGC mediums, on a short scale guitar, is probably not a problem at all. I think Eric Skye was playing mediums on his signature 00 for some time, but I really don’t know what he’s using now –